Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs
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چکیده
منابع مشابه
Calcineurin does not mediate exercise-induced increase in muscle GLUT4.
Exercise induces a rapid increase in expression of the GLUT4 isoform of the glucose transporter in skeletal muscle. One of the signals responsible for this adaptation appears to be an increase in cytosolic Ca(2+). Myocyte enhancer factor 2A (MEF2A) is a transcription factor that is involved in the regulation of GLUT4 expression. It has been reported that the Ca(2+)-regulated phosphatase calcine...
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Background. The accumulation of excess triglyceride in the liver and a decrease in brown adipose tissue is related to the fatty liver disease. Regular physical activity can take part in regulating fat oxidation and inhibiting fat accumulation by creating and releasing some myokines. Nevertheless, the effectiveness of each training method in this regard is still not certain. Objective(s). This ...
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Exercise upregulates the expression of NR4A receptors, which are involved in regulation of glucose and fatty acid utilization genes in skeletal muscle. The aims of our study were 1) to determine the role of local contractile activity on NR4A mRNA expression in skeletal muscle during exercise; and 2) to elucidate the mechanisms underlying the induction of NR4A mRNA expression in response to musc...
متن کاملComments on Point:Counterpoint: Exercise training does/does not induce vascular adaptations beyond the active muscle beds
TO THE EDITOR: Animal investigations permit invasive techniques and a spatial and temporal resolution not feasible in humans. Thus structural and functional adaptations to exercise training within the muscle resistance vasculature (i.e., arterioles) can be observed directly and related to blood flow within the same muscle (3–5). This approach is powerful because the hemodynamic response differs...
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ژورنال
عنوان ژورنال: Metabolism
سال: 2013
ISSN: 0026-0495
DOI: 10.1016/j.metabol.2013.05.021